With a heatwave sweeping over New York, the match was played under a partially closed roof on the hottest day of the tournament so far, with temperatures expected to rise to 35C on Wednesday.
Both players looked physically and emotionally drained as Medvedev eventually wrapped up the match after two hours and 48 minutes before comparing the "brutal" conditions to the weather he experienced during the 2020 Tokyo Olympics.
"The only good thing I see in these conditions is that both [players] suffer. It's tough for both of us," he said in his on-court interview.
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